Q32 Bio: Submission Of Matters To A Vote Of Security Holders

Item 5.07. Submission of Matters to a Vote of Security Holders. During the 2026 Annual Meeting of Stockholders (the “Annual Meeting”) of Q32 Bio Inc. (the “Company”), the Company’s stockholders considered and voted on the three proposals set forth below, each of which is described in greater detail in the Company’s definitive proxy statement filed with the Securities and Exchange Commission on April 30, 2026 in connection with the Annual Meeting. Represented in person or by proxy at the Annual Meeting were 11,833,800 shares of the Company’s common stock, par value $0.0001 per share (“Common Stock”), out of 15,629,463 shares of Common Stock entitled to vote at the Annual Meeting, or 75.71% of the total number of shares of Common Stock outstanding as of April 15, 2026, the record date. The final voting results of the matters submitted to the stockholders’ vote are set forth below. Proposal No. 1 - Election of Class II Directors: The stockholders of the Company elected Kathleen LaPorte, Jodie Morrison, and Arthur Tzianabos, Ph.D., as Class II directors of the Company, for a three-year term ending at the annual meeting of stockholders to be held in 2029 and until his or her successor has been duly elected and qualified, or until his or her earlier death, resignation or removal. The results of the stockholders’ vote with respect to the election of the Class II directors were as follows: Name Votes For Votes Withheld Broker Non-Votes Kathleen LaPorte 7,187,421 1,428,633 3,217,746 Jodie Morrison 8,591,626 24,428 3,217,746 Arthur Tzianabos, Ph.D. 8,310,837 305,217 3,217,746 Proposal No. 2 - Ratification of the Appointment of Ernst & Young LLP as the Company’s Independent Registered Public Accounting Firm for the Fiscal Year Ending December 31, 2026: The stockholders ratified the appointment of Ernst & Young LLP as the Company’s independent registered public accounting firm for the fiscal year ending December 31, 2026. The results of such vote were as follows: Votes For Votes Against Abstentions Broker Non-Votes 11,821,046 7,909 4,845 — Proposal No. 3 - Non-Binding, Advisory Vote on the Compensation of the Company’s Named Executive Officers: The stockholders of the Company approved, on a non-binding, advisory basis, the compensation of the Company’s named executive officers. The results of the stockholders’ vote with respect to such approval were as follows: Votes For Votes Against Abstentions Broker Non-Votes 8,072,067 400,598 143,389 3,217,746 SIGNATURES Pursuant to the requirements of the Securities Exchange Act of 1934, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized. Q32 BIO INC. Date: June 16, 2026 By: /s/ Jodie Morrison Name: Jodie Morrison Title: Chief Executive Officer

Q32 Bio: Submission Of Matters To A Vote Of Security Holders

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